We are dealing with primary and secondary tumors specifically in the liver, taking care of primary tumors emerges from the tumor itself.
What is RFA?
Radio frequency energy by a generator directed to the patient that causes the cells adjacent to the device to spin. This spinning cause frictional heat and disperses across the tissue adjacent to the device, which leads to cell death.
Benefit to the patient
Metastatic Colorectal Cancer
There are 400,000 colorectal cancer patients and it’s projected that 60% to 70% of patients develop metastasis.
30% of patients with metastasis will present liver-only disease.
Only 20-25% of patients with liver metastasis are candidates for surgical resection.
45% of patients that die from Mcrc will die with liver-only disease.
Microwave vs RF
- Microwave is much faster
- Microwave is simpler to insert, visualize and utilize
- Microwave includes less heat-sink effects
- The basic challenge of microwave techniques is to overcome the reflection of microwave, which reaches 80% of the generated waves. This reflected part can be absorbed by the transmission system and will cause the transmission system to heat up. This reflection problem is reducible through careful antenna design, in the case of AngioDynamics MW systems:
- has a ceramic tip and a water cooling system
- non-conductive stainless steel
- Uses focused energy delivering by a feed point
These traits lead to less reflections and hence better performance.
Nano knife IRE surgical ablation system is the first to use Irreversible Electroporation also know as IRE to ablate soft tissue. Two or more nano knife IRE disposable electrodes are positioned in or around the area to be ablated. And an electric field created between them in a series of microsecond pulses, which induces cell death in the encompassed soft tissue. Unlike trio ablation or microwave ablation which use heat to destroy tissue, the IRE system treats without exposing the tissue to extreme cold or heat, eliminating the cause of treatment failure and possible damage to tissues adjacent to the treated area.
Treatment using nano knife ablation ablating a 2-centimeter diameter region is typically 5 minutes.
The IRE system is minimally invasive, operated under general anesthesia with ultrasound or CT guidance. Pre-operative imaging allows precise calculation of tissue shape and volume to be ablated and aids the planning for appropriate positioning for the nano knife IRE electrodes. The patient can usually be released from the hospital at the same day.